Gene information
Official symbol CDH2
Official full name cadherin 2
Gene type protein-coding gene
Chromosome18q12.1
Alias symbolCDHN; CD325
Previous symbolNCAD
Gene familyCD molecules; Type I classical cadherins
Resources
Entrez Gene 1000
HGNC HGNC:1759
Ensembl ENSG00000170558
Vega OTTHUMG00000059940
UCSC uc002kwg.3
GO terms: 83 records
GO Description Category LogP Number of genes Detail
GO:0001568 blood vessel development GO Biological Processes -43.2646440 106 More
GO:0001667 ameboidal-type cell migration GO Biological Processes -17.0771232 40 More
GO:0001944 vasculature development GO Biological Processes -42.3240404 107 More
GO:0002064 epithelial cell development GO Biological Processes -8.05661081 27 More
GO:0002065 columnar/cuboidal epithelial cell differentiation GO Biological Processes -7.52899002 17 More
GO:0002067 glandular epithelial cell differentiation GO Biological Processes -3.22341771 8 More
GO:0003309 type B pancreatic cell differentiation GO Biological Processes -2.72529058 5 More
GO:0005509 calcium ion binding GO Molecular Functions -14.7764642 80 More
GO:0005911 cell-cell junction GO Cellular Components -3.41801827 38 More
GO:0005912 adherens junction GO Cellular Components -2.24960527 8 More
GO:0005925 focal adhesion GO Cellular Components -8.40302345 46 More
GO:0005938 cell cortex GO Cellular Components -2.49954036 24 More
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO Biological Processes -3.60984508 9 More
GO:0007420 brain development GO Biological Processes -11.5572036 75 More
GO:0009581 detection of external stimulus GO Biological Processes -2.05740021 12 More
GO:0009582 detection of abiotic stimulus GO Biological Processes -2.39356289 13 More
GO:0009612 response to mechanical stimulus GO Biological Processes -18.7627330 44 More
GO:0010001 glial cell differentiation GO Biological Processes -13.0211768 33 More
GO:0010975 regulation of neuron projection development GO Biological Processes -5.89330331 41 More
GO:0014032 neural crest cell development GO Biological Processes -11.9399165 15 More
GO:0014033 neural crest cell differentiation GO Biological Processes -12.2997127 24 More
GO:0019827 stem cell population maintenance GO Biological Processes -2.86048070 7 More
GO:0019898 extrinsic component of membrane GO Cellular Components -2.13392265 23 More
GO:0019900 kinase binding GO Molecular Functions -6.03057706 62 More
GO:0019901 protein kinase binding GO Molecular Functions -6.66055444 59 More
GO:0021537 telencephalon development GO Biological Processes -6.21909725 29 More
GO:0021543 pallium development GO Biological Processes -4.55337429 20 More
GO:0021987 cerebral cortex development GO Biological Processes -4.14759222 15 More
GO:0030027 lamellipodium GO Cellular Components -1.61995196 15 More
GO:0030055 cell-substrate junction GO Cellular Components -9.04790297 48 More
GO:0030111 regulation of Wnt signaling pathway GO Biological Processes -7.94227486 39 More
GO:0030178 negative regulation of Wnt signaling pathway GO Biological Processes -7.69726068 26 More
GO:0030855 epithelial cell differentiation GO Biological Processes -14.2408795 69 More
GO:0030900 forebrain development GO Biological Processes -11.1545964 48 More
GO:0031016 pancreas development GO Biological Processes -6.43498850 15 More
GO:0031018 endocrine pancreas development GO Biological Processes -4.66781085 9 More
GO:0031252 cell leading edge GO Cellular Components -1.97716247 28 More
GO:0031344 regulation of cell projection organization GO Biological Processes -8.91314416 62 More
GO:0034330 cell junction organization GO Biological Processes -7.96624809 49 More
GO:0035239 tube morphogenesis GO Biological Processes -44.2569269 123 More
GO:0035270 endocrine system development GO Biological Processes -10.2307745 25 More
GO:0035883 enteroendocrine cell differentiation GO Biological Processes -2.54763391 5 More
GO:0042063 gliogenesis GO Biological Processes -20.3412228 47 More
GO:0042692 muscle cell differentiation GO Biological Processes -15.1559811 45 More
GO:0043408 regulation of MAPK cascade GO Biological Processes -57.2547066 142 More
GO:0043410 positive regulation of MAPK cascade GO Biological Processes -49.4744054 112 More
GO:0044853 plasma membrane raft GO Cellular Components -18.4542052 33 More
GO:0045121 membrane raft GO Cellular Components -30.0775030 71 More
GO:0045177 apical part of cell GO Cellular Components -8.17813885 46 More
GO:0045211 postsynaptic membrane GO Cellular Components -5.83105498 30 More
GO:0048514 blood vessel morphogenesis GO Biological Processes -39.8784810 93 More
GO:0048762 mesenchymal cell differentiation GO Biological Processes -16.1250183 37 More
GO:0048863 stem cell differentiation GO Biological Processes -16.2106470 36 More
GO:0048864 stem cell development GO Biological Processes -12.7283120 16 More
GO:0050770 regulation of axonogenesis GO Biological Processes -3.56457741 17 More
GO:0050803 regulation of synapse structure or activity GO Biological Processes -6.38009123 27 More
GO:0050804 modulation of chemical synaptic transmission GO Biological Processes -15.2260557 60 More
GO:0050807 regulation of synapse organization GO Biological Processes -6.08931613 26 More
GO:0050808 synapse organization GO Biological Processes -6.17744712 32 More
GO:0050839 cell adhesion molecule binding GO Molecular Functions -14.4506551 68 More
GO:0051146 striated muscle cell differentiation GO Biological Processes -10.9431474 33 More
GO:0060322 head development GO Biological Processes -11.995356 79 More
GO:0060341 regulation of cellular localization GO Biological Processes -10.5933083 72 More
GO:0060485 mesenchyme development GO Biological Processes -18.0238 46 More
GO:0060828 regulation of canonical Wnt signaling pathway GO Biological Processes -5.69122875 29 More
GO:0061061 muscle structure development GO Biological Processes -23.2569142 77 More
GO:0090090 negative regulation of canonical Wnt signaling pathway GO Biological Processes -6.26985667 21 More
GO:0090497 mesenchymal cell migration GO Biological Processes -8.76593708 16 More
GO:0097060 synaptic membrane GO Cellular Components -5.94418548 20 More
GO:0097150 neuronal stem cell population maintenance GO Biological Processes -4.69888733 5 More
GO:0098609 cell-cell adhesion GO Biological Processes -15.7963965 69 More
GO:0098727 maintenance of cell number GO Biological Processes -2.81522024 7 More
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules GO Biological Processes -5.22391282 28 More
GO:0098793 presynapse GO Cellular Components -4.56552653 42 More
GO:0098857 membrane microdomain GO Cellular Components -30.8181788 72 More
GO:0098889 intrinsic component of presynaptic membrane GO Cellular Components -4.93822812 13 More
GO:0098984 neuron to neuron synapse GO Cellular Components -1.42277265 10 More
GO:0099056 integral component of presynaptic membrane GO Cellular Components -4.69230219 12 More
GO:0099175 regulation of postsynapse organization GO Biological Processes -4.87425615 14 More
GO:0099177 regulation of trans-synaptic signaling GO Biological Processes -15.1793607 60 More
GO:0099572 postsynaptic specialization GO Cellular Components -2.67743186 13 More
GO:0120035 regulation of plasma membrane bounded cell projection organization GO Biological Processes -8.54789693 60 More
GO:1905475 regulation of protein localization to membrane GO Biological Processes -3.01117711 17 More
Drug-Gene interaction
view
Related drugs: 2 records
Drug name Interaction type Source PMID View
adh-1 TdgClinicalTrial view
methadone PharmGKB view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
Chr18:29413308 hypomethylation epigenomics ischemic cardiac events[prognosis (bad)] myocardial infarction Thunders M et al. Epigenetics. 2019
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